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Fig 1.

Design of the case-control study.

PAC: pre-anaesthesia clinic, DRP: drug-related problem.

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Fig 1 Expand

Fig 2.

Pre-anaesthesia clinic (PAC), routine care procedure.

ECG: Electrocardiography.

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Fig 3.

Participant flow diagram.

DRP: Drug-related problem.

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Table 1.

Participant characteristics. Frequencies, proportions, means, SDs and OR are presented. Not applicable (NA): Missing information due to lack of data in clinical records. BMI: body mass index, DRP: drug related problem, CCI: Charlson Comorbidity Index, ASA: American Society of Anesthesiologists, OR: odds ratio, SD: standard deviation.

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Fig 4.

MediPORT tool.

Calculation of patient risk for developing a drug-related problem requiring pharmaceutical care at hospital admission. 5VM: 5 Variable Model, 2VM: 2 Variable Model, DRP: drug-related problem, PAC: pre-anesthesia clinic, BMI: body mass index, eGFR: estimated glomerular filtration rate.

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Fig 5.

Renal function.

Risks of developing a drug-related problem among different renal function levels and sex within the 2VM and 5VM. f: female, m: male, DRP: drug-related problem.

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Fig 6.

Receiver operating characteristic (ROC) curves of the predictive models obtained in the training sets.

2VM: 2 Variable Model, 5VM: 5 Variable Model.

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Fig 7.

Receiver operating characteristic (ROC) curves of the predictive models obtained in the validation sets.

2VM: 2 Variable Model, 5VM: 5 Variable Model.

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Fig 8.

Calibration plot of the mediPORT tool.

Distribution of predicted probabilities for patients with and without the outcome (drug-related problems). 2VM: 2 Variable Model, 5VM: 5 Variable Model.

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Fig 8 Expand