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Fig 1.

A map of the location of provinces in China.

Color-coded regions are cases of scrub typhus in the top 8 provinces, China, 2006–2018 (Dark colors indicate a high number of scrub typhus cases and light colors indicate a low number of scrub typhus cases). This map was created by ArcGIS software (version 10.6, ESRI Inc.; Redlands, CA, USA). Homepage of ArcGIS software was https://www.esri.com/.

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Table 1.

Epidemiologic features of scrub typhus cases in China, 2006 −2018.

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Table 2.

Reported cases and annual average incidence of scrub typhus in 31 provinces, China, 2006–2018.

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Table 3.

Sex, age and geographic area characteristics description of scrub typhus cases in China, 2006 −2018.

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Fig 2.

Sequence map of monthly number of scrub typhus cases in China from 2006 to 2018.

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Fig 3.

Sequence map of monthly number of scrub typhus cases after first-order seasonal difference with one-period of 12 in China from 2006 to 2018.

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Table 4.

Goodness of fits for the SARIMA models corresponding to different choices of p, q and P, Q.

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Fig 4.

Plot of autocorrelation function (ACF) after a first-order seasonal difference.

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Fig 5.

Plot of partial autocorrelation function (PACF) after a first-order seasonal difference.

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Fig 6.

Autocorrelation function (ACF) and partial autocorrelation function (PACF) of the residuals series of the SARIMA (1, 0, 2) (1, 1, 1)12 model.

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Table 5.

Comparison of observed number of scrub typhus cases and corresponding out-of-sample predicted values from January to December in 2019 by the SARIMA (1, 0, 2) (1, 1, 1) 12 model.

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Fig 7.

SARIMA (1, 0, 2) (1, 1, 1)12 model fitting, verification and forecasting of scrub typhus in China from January 2006 to December 2018 (UCL, upper confidence limit; LCL, low confidence limit).

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