Fig 1.
Phylogenetic tree indicating the relationship between six major VoCs and the reference genome for SARS-CoV-2.
Fig 2.
Predicted structures of the 5′ and 3′UTRs and the frameshifting stimulatory element (FSE) of SARS-CoV-2.
Fig 3.
Flowchart describing the methods employed in our previous work.
Table 1.
Number of complete, high coverage viral genomes collected per Variant of Concern.
Fig 4.
Flowchart describing the methods employed to analyze each Variant of Concern.
Fig 5.
Venn diagram showing the distribution of mutations found in the Alpha variant according to outbreak.info and this work.
Fig 6.
Venn diagram showing the distribution of mutations found in the Beta variant according to outbreak.info and this work.
Fig 7.
Venn diagram showing the distribution of mutations found in the Gamma variant according to outbreak.info and this work.
Fig 8.
Venn diagram showing the distribution of mutations found in the Delta variant according to outbreak.info and this work.
Fig 9.
Venn diagram showing the distribution of mutations found in the Omicron variant according to outbreak.info and this work.
Fig 10.
Venn diagram showing the distribution of mutations found in the BA2 variant according to outbreak.info and this work.
Fig 11.
Caterpillar plots comparing non-coding, synonymous, and non-synonymous mutations identified by this work (top row) against those non-synonymous mutations catalogued by outbreak.info (bottom row).
Panels A-F: Alpha, Beta, Gamma, Delta, Omicron and Omicron BA2 VoC mutation profiles.
Fig 12.
Wildtype (left) and mutated (right) versions of a structure predicted to occur within ORF3a.
The red nucleotides indicate the mutated position.
Fig 13.
Wildtype (left) and mutated (right) versions of a structure predicted to occur within ORF3a.
The red nucleotides indicate the mutated position. Note that this structure prediction is for three adjacent mutated nucleotides.