Table 1.
Baseline demographics.
Table 2.
CSF markers at baseline.
Fig 1.
Longitudinal trajectories of B-SIT over time in participants with Parkinson’s disease and either normal olfactory function or hyposmia at baseline.
Bold lines represent the predicted trajectory in each group.
Fig 2.
Longitudinal trajectories of cognitive, motor, autonomic and psychiatric scores over time in participants with Parkinson’s disease depending on olfactory function and amyloid status.
Bold lines represent the predicted trajectory in each group. MMSE, mini-mental state examination. ADAS DW recall, Alzheimer’s Disease Assessment Scale-Cognitive Subscale delayed word recall. AQT, A Quick Test. HADS, hospital anxiety and depression scale. SCOPA-AUT, Scales for Outcomes in Parkinson’s disease – Autonomic Dysfunction. UPDRS-III, Unified Parkinson’s Disease Rating Scale Part III. AB + , amyloid-positive. AB-, amyloid-negative.
Fig 3.
Kaplan-Meier curve demonstrating probability of converting to dementia in Parkinson’s disease depending on olfactory function at baseline.
Table 3.
Multivariate Cox proportional regression hazard modelling.