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Fig 1.

Workflow and structure of the insulin pump.

(a) flow chart of insulin pump work structure. (b) PH 300 insulin pump experimental platform for algorithm development.

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Fig 1 Expand

Fig 2.

Comparison of the transmission structure of the insulin pump.

(a) one-stage screw drive. (b) two-stage screw drive.

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Fig 2 Expand

Table 1.

Design of insulin infusion regimen for experimental verification.

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Table 1 Expand

Fig 3.

Schematic diagram of experimental setup for in vitro study.

(a) model. (b) entity.

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Fig 3 Expand

Table 2.

Performance comparison between theoretical and actual injection doses.

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Table 2 Expand

Fig 4.

Boxplot of theoretical and actual injection doses.

(a) 1U and 2U. (b) 3U and 4U. (c) 5U-7U. (d)8U-10U.

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Fig 4 Expand

Table 3.

Comparison of single infusion accuracy between single-stage and two-stage pumps.

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Table 3 Expand

Table 4.

Accuracy comparison of single-stage and two-stage pumps for low base rate infusion.

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Table 4 Expand

Fig 5.

The design of the brushless direct current motor (BLDCM) closed-loop speed regulating system.

(a) BP neural network combined with PID controller structure. (b) BLDCM closed-loop single-speed system is controlled based on BP-PID.

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Fig 5 Expand

Fig 6.

Simulation performance and control effect of BP-PID.

(a) motor speed waveform with standard PID. (b) motor speed waveform with BP-PID. (c) electromagnetic torque waveform with standard PID. (d) electromagnetic torque waveform with BP-PID. (e) comparison of motor speed overshoot between standard PID and BP-PID. (f) PID adaptive parameter waveform diagram.

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Fig 6 Expand

Fig 7.

Prediction (a-d) and infusion deviation (e-f) results under different training sets and test sets.

(a) and (e) training set 90%, test set 10%. (b) and (f) training set 85%, test set 15%. (c) and (g) training set 80%, test set 20%. (d) and (h) training set 75%, test set 25%.

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Fig 7 Expand

Table 5.

LSTM parameter combination by using the grid search method.

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Table 5 Expand

Fig 8.

Accuracy and loss of LSTM model training and testing.

(a) LSTM training and testing accuracy. (b) LSTM training and testing losses.

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Fig 8 Expand