Table 1.
Demographic, clinical, and MRI characteristics of the MS subjects.
Fig 1.
Representative depiction of: A) T1-weighted B) T2 FLAIR, C) retroactive T1 map, and D) MTR map.
Fig 2.
MS lesion correlation between T1 and MTR, values are standardized to Z-scores. MTR is plotted as inverse (-MTR).
Table 2.
Correlation of T1 and MTR values of lesions expressed as percentiles with EDSS, BPF, and disease duration.
Table 3.
Correlation of lesion volume stratified by different T1 thresholds with various measures of MS disability.
Table 4.
Ordinal regression analysis of T1 and MTR associations with EDSS adjusted for age.
Fig 3.
A) Comparison of mean and maximum T1 of lesions across different severity classifications of EDSS and B) Multiple Pairwise Comparisons Test of the ranks from the Kruskal-Wallis Test (±SD).
The degree of overlap between lower and higher ranks of T1 values is indicated, with EDSS 0-2 and EDSS 4.5-6.5 having no overlap.