Fig 1.
Flow chart for data selection.
Abbreviation: KNHANES, Korea National Health and Nutrition Survey.
Table 1.
Summary of study participants by diabetes and dyslipidemia.
Table 2.
Summary of IR indices across quartiles.
Fig 2.
Mutual information and ROC curve of diabetes (A, B) and dyslipidemia (C, D).
Abbreviation: ROC, receiver operating characteristic; AUC, area under the curve. BMI, body mass index; WC, waist circumference; WHtR, waist-to-height ratio; SBP, systolic blood pressure; FBG, fasting blood glucose; HbA1c, hemoglobin A1c; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TCHOL, total cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; TyG index, triglyceride-glucose index; TG/HDL, triglyceride-to-high-density lipoprotein cholesterol ratio.
Fig 3.
A directed acyclic graph of Bayesian network obtained through hill-climbing learning algorithm with threshold
= 0.75 by model averaging over 1,000 networks. Arc thickness represents the strength of association based on the Akaike Information Criterion (AIC). Abbreviation: BMI, body mass index; WC, waist circumference; WHtR, waist-to-height ratio; SBP, systolic blood pressure; FBG, fasting blood glucose; HbA1c, hemoglobin A1c; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TCHOL, total cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; TyG index, triglyceride-glucose index; TG/HDL ratio, triglyceride-to-high-density lipoprotein cholesterol ratio.
Fig 4.
Markov blankets of HOMA-IR (A), TG/HDL ratio (B), and TyG index (C).
Abbreviation: BMI, body mass index; WC, waist circumference; WHtR, waist-to-height ratio; SBP, systolic blood pressure; FBG, fasting blood glucose; HbA1c, hemoglobin A1c; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TCHOL, total cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; TyG index, triglyceride-glucose index; TG/HDL, triglyceride-to-high-density lipoprotein cholesterol ratio.
Fig 5.
Conditional probabilities of diabetes (A) and dyslipidemia (B) across the quartile groups (Q1-Q4) of HOMA-IR, TyG index, and TG/HDL ratio.
Abbreviation: HOMA-IR, homeostasis model assessment of insulin resistance; TyG index, triglyceride-glucose index; TG/HDL, triglyceride-to-high-density lipoprotein cholesterol ratio; Q1, 1st quartile group; Q2, 2nd quartile group; Q3, 3rd quartile group; Q4, 4th quartile group.
Fig 6.
Conditional probabilities of diabetes with obesity (based on BMI) given the TyG index (A) and HOMA-IR (B), and conditional probabilities of dyslipidemia with hypertension given the TG/HDL ratio (C) and TyG index (D).
Abbreviation: HOMA-IR, homeostasis model assessment of insulin resistance; TyG index, triglyceride-glucose index; TG/HDL, triglyceride-to-high-density lipoprotein cholesterol ratio; BMI, body mass index.