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Fig 1.

Extreme borrowing boundary of Fujikawa et al.’s tuning parameters.

Extreme borrowing boundary for different stratum counts I and per-stratum patient counts ni and the upper bound of the parameter space for the grid search algorithm.

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Table 1.

Outcome scenarios sets.

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Table 1 Expand

Table 2.

Run time of 1000 iterations in a pilot study.

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Table 2 Expand

Table 3.

Estimation of the total run time for Part I of the comparison study.

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Table 3 Expand

Table 4.

Estimation of the total run time for Part I of the comparison study.

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Table 4 Expand