Fig 1.
PRISMA flow diagram showing literature search and study selection.
Table 1.
Characteristics of included studies in the systematic review and meta-analyses.
Table 2.
Allergic, SARs, anaphylactic and fatal reactions following BPG injection among ARF and RHD patients.
Table 3.
Subgroup analysis of incidence of SARs following BPG injection.
Fig 2.
Incidence of SARs following BPG injection, per 10,000 cases.
Fig 3.
Incidence of SARs per 10,000 BPG injections among ARF and RHD patients.
Table 4.
Characteristics of patients experiencing fatal reactions following BPG injection.
Fig 4.
Incidence of fatal reactions following BPG injection per 10,000 cases.
Table 5.
Leave-one-out sensitivity analysis for the incidence of SARs following BPG injection among ARF/RHD patients after removal of each study one at a time.