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Table 1.

Cardiovascular adverse events grouped into 8 narrow categories of SMQs according to MedDRA 24.0.

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Table 1 Expand

Fig 1.

The bar plot shows the number of reports with cardiovascular AEs for different JAKinibs treatment.

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Fig 1 Expand

Fig 2.

The time trend of cardiovascular AEs.

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Fig 2 Expand

Table 2.

The clinical characteristics of cardiovascular AEs.

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Table 2 Expand

Fig 3.

Disproportionality analysis of JAKinibs-related cardiovascular AEs compared to the full database(ROR: reporting odds ratio, ROR025: The lower limit of the 95% CI for ROR, ROR075: The upper limit of the 95%CI for ROR).

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Fig 3 Expand

Fig 4.

Disproportionality analysis of JAKinibs-related cardiovascular AEs compared to TNF-α inhibitors(ROR: reporting odds ratio, ROR025: The lower limit of the 95% CI for ROR, ROR075: The upper limit of the 95%CI for ROR).

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Fig 4 Expand