Fig 1.
Global burden of disease map for ADD, 1990-2021.
(A) Annual change in deaths per 100,000 people for all sexes and all ages (B) Annual change in DALYs per 100,000 people for all sexes and all ages (C) Annual change in YLDs per 100,000 people for all sexes and all ages.
Table 1.
All-age numbers and ASR per 100,000 of incidence, prevalence, deaths, DALYs, YLDs and YLLs for ADD and total percentage change by sex in China, 1990-2021.
Table 2.
All-age numbers and ASR per 100,000 of incidence, prevalence, deaths, DALYs, YLDs and YLLs for ADD and total percentage change by sex globally, 1990-2021.
Fig 2.
Disease burden of ADD in different age groups and by sex in China and globally in 2021.
(A) The numbers of incidence in China (B) The numbers of incidence globally (C) ASIR in China (D) Global ASIR (E) The numbers of prevalence in China (F) The numbers of prevalence globally (G) ASPR in China (H) Global ASPR.
Fig 3.
Trends in all-age numbers and ASRs of incidence, deaths and DALYs for ADD by sex, 1990-2021.
The numbers on the left correspond to the bar graph, and the rates on the right correspond to the curve graph. (A) Incidence number and rate in China (B) Global incidence number and rate (C) Deaths number and rate in China (D) Global deaths number and rate (E) DALYs number and rate in China (F) Global DALYs number and rate.
Table 3.
AAPC values of ASIR and ASDR for ADD in China and globally, 1990-2021.
Fig 4.
Joinpoint regression analysis of ADD among all sexes in China and Globally, 1990-2021.
An asterisk in the upper right corner of an APC value means that the P-value for that APC value is less than 0.05. (A) Segmental trend of ASIR in China (B) Segmental trend of global ASIR (C) Segmental trend of ASDR in China (D) Segmental trend of global ASDR.
Table 4.
Percentage of aging, population and epidemiological change for ADD by sex in China and globally, 1990-2021.
Fig 5.
Decomposition analysis of ADD by sex according to aging, population and epidemiological change in China and Globally, 1990-2021.
The black dots indicate the overall trend resulting from adding the contributions of the three components. (A) Distribution of causes of deaths in China (B) Global distribution of causes of deaths (C) Distribution of causes of incidence in China (D) Global distribution of causes of incidence.
Fig 6.
Attributable risk factors for ADD by sex in China and globally, 1990 and 2021.
(A) Risk factors for both sexes in China, 1990 (B) Risk factors for females in China, 1990 (C) Risk factors for males in China, 1990 (D) Risk factors for both sexes globally, 1990 (E) Risk factors for females globally, 1990 (F) Risk factors for males globally, 1990 (G) Risk factors for both sexes in China, 2021 (H) Risk factors for females in China, 2021 (I) Risk factors for males in China, 2021 (J) Risk factors for both sexes globally, 2021 (K) Risk factors for females globally, 2021 (L) Risk factors for males globally, 2021.
Table 5.
All-age numbers and ASR per 100,000 of DALYs, YLDs and YLLs of attributable risk factors for ADD by sex in China and globally in 2021.
Fig 7.
Trend projections of ASDR and ASIR for ADD by sex in China and Globally over the next 15 years.
The red line represents the actual trend from 1990 to 2021, while the yellow dotted line and the corresponding shaded area represent the forecast trend and its 95% CI. (A) Prediction of ASDR for female in China (B) Prediction of ASDR for global female (C) Prediction of ASDR for male in China (D) Prediction of ASDR for global male (E) Prediction of ASIR for female in China (F) Prediction of ASIR for global female (G) Prediction of ASIR for male in China (H) Prediction of ASIR for global male.