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Fig 1.

Directed acyclic graph demonstrating the relations between measured and unmeasured confounding variables, osteoarthritis, and cardiovascular disease.

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Table 1.

Description of the study sample by exposure status and sex (N = 1,838,434)a.

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Fig 2.

Participant flow chart.

Main results.

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Fig 3.

Cumulative incidence curves of cardiovascular disease for men and women with and without hip or knee osteoarthritis.

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