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Fig 1.

Experimental flow chart of the study.

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Fig 2.

OF2 isolate phylogenetic tree generated by using MEGA 11 software related to B. amyloliquefaciens.

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Table 1.

GC-MS results of the 23 secondary metabolites present in the extract of OF2 isolate, identified using GC-MS QP2010 Plus (Shimadzu, Japan).

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Fig 3.

The UV-VIS spectrophotometric analysis of AgNPs, synthesized by using OF2 secondary metabolites extract, revealed distinct Plasmon resonance peaks at 420nm.

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Fig 4.

SEM micrograph of AgNPs at 1000x magnification (A) and EDS elemental spectrum of biosynthesized AgNPs (B).

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Fig 5.

The FTIR spectrum (A) and Zeta potential (B) of AgNPs synthesized by using OF2 secondary metabolites extract.

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Table 2.

Antibacterial activity of OF2 secondary metabolites extract and OF2-AgNPs determined by agar well diffusion method at 2 mg/mL concentration (S1 Table).

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Table 2 Expand

Fig 6.

DDPH radicals scavenging activity (%) of B. amyloliquefaciens derived secondary metabolites (OF2) and their synthesized AgNPs (OF2-AgNPs), ascorbic acid was used as a reference compound.

The statistical significance level represents *p<0.05 and **p<0.01 (S2 Table).

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Fig 7.

The latency time (seconds) of OF2 secondary metabolites extract and its mediated AgNPs at various concentrations, diclofenac sodium was used as standard (Std) while normal saline (NS) as a control.

The statistical significance level represents *p<0.05, **p<0.01, and ***p<0.001 (S4 Table).

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