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Fig 1.

Percentage of central and obstructive apneas during sleep.

Comparison of the percentage of sleep apnea of central (CSA) and obstructive (OSA) origin among C57BL/6J mice (n = 9), Ts65Dn mice (n = 9), model of Down syndrome, and euploid control mice (n = 11), recorded during non-rapid-eye-movement sleep (NREMS) and rapid-eye-movement sleep (REMS) inside the whole-body plethysmography chamber. Data are also presented in Bartolucci et al. 2021 [24].

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Fig 1 Expand

Fig 2.

Examples of central sleep apneas.

Panels A and B show representative examples of raw tracings corresponding to central sleep apneas (CSA). Each panel shows the differential pressure signal (VENT, corresponding to mouse respiratory patter), the diaphragm electromyogram (DIA), the electroencephalogram (EEG), and the nuchal electromyogram (nEMG).

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Fig 2 Expand

Fig 3.

Examples of obstructive sleep apneas.

Panels A and B show representative examples of raw tracings corresponding to obstructive sleep apneas (OSA). Each panel shows the differential pressure signal (VENT, corresponding to mouse respiratory pattern), the diaphragm electromyogram (DIA), the electroencephalogram (EEG), and the nuchal electromyogram (nEMG).

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Fig 3 Expand