Table 1.
MAPS Oral Wound Healing Index Quantification.
Fig 1.
The “MAPS” Wound Healing Index.
A comprehensive framework for categorizing the key parameters of wound healing.
Table 2.
Horizontal bone gain outcome measurements using Cone Beam Computed Tomography (CBCT).
Fig 2.
Pearson’s correlation between bone gain at 3 mm below the edentulous crest (A).
Bone gains exploratory plots show approximately normally distributed (B).
Table 3.
Intra-examiner agreement summary statistics.
Table 4.
Inter-examiner agreement summary statistics.
Table 5.
Inter-reader agreement of each score.
Fig 3.
MAPS score changes over time at 3-, 10-, 21 days, and 5 months.
Fig 4.
Case demonstration of compromised healing after guided bone regeneration procedure.
Top row shows clinical intraoral photography from baseline (BL), 3 days (D3), 10 days (10D), 21 days (D21), and 5 months (5M). Bottom row shows CBCT bone width measurements at baseline (BL), 5 months (5M). There is evidence of inferior bone gain seen in clinical photos over time due to compromised healing and shown in bone loss measurements in the follow-up CBCT.
Fig 5.
Case demonstration of favorable healing after guided bone regeneration procedure.
Top row shows clinical intraoral photography from baseline (BL), 3 days (D3), 10 days (10D), 21 days (D21), and 5 months (5M). Bottom row shows CBCT bone width measurements at baseline (BL), 5 months (5M). There is clear evidence of superior bone gain seen in clinical photos over time due to optimal healing and shown in bone gain measurements in the follow-up CBCT.
Fig 6.
Scatterplot of mean MAPS scores with bone gain at 3 mm at different time points.
The color scale bar indicates bone gain, where dark blue can be seen as negative bone gain (up to -2.5 mm), light blue no gain ( ~ 0 mm), dark green mild bone gain (up to 2.5 mm), light green moderate bone gain (up to 5 mm), and yellow high bone gain (>5 mm). Higher M,A, P at any time point is associated with higher bone gain.
Fig 7.
Multiple Pearson’s correlations between bone gain and MAPS scores at 1, 3, and 5 mm at 10 days (A-C) and 21 days (D-F).
There is statistical significance of bone gain at 1, 3, and 5 mm at 10 and 21 days when compared to the MAPS score (p-value < 0.05). MAPS score correlated with bone changes after GBR procedures, indicating its potential for estimating hard tissue regenerative outcomes.
Fig 8.
Lower (scores of 1-2), and higher (scores of 3-4) MAPS scores were correlated with bone gain measured in CBCT at 1, 3, and 5 mm.
There is statistical significance for bone gain at 3 mm when correlated with the grouped low and high MAPS scores (p-value < 0.005).
Table 6.
Fit linear model at each time point with an individual average score of M, A, P, and from baseline to 5 months follow up at 3 mm level bone gain.
Table 7.
Fit Model Summary with dependent variables of the individual average score of M, A, P, and from baseline to 5 months follow up at 3 mm level bone gain.
Table 8.
Final predictive model.