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Fig 1.

Flow diagram for the identification of studies included.

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Fig 2.

Forest plot of the improvement in primary endpoints.

(a). Improvement rate of chest CT (b). Severe conversion rate of mild/moderate patients (c). Mortality rate of severe/critical patients (d). Negativity time of nucleic acid.

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Fig 3.

Forest plot of the second endpoint of the clinical symptom improvement.

(a). Rate of fever reduction; (b). Time to the reduction of fever; (c). Improvement rate of cough; (d). Time to improvement of cough; (e). Improvement rate of breathless; (f). Improvement rate of fatigue.

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Fig 4.

Forest plot of inflammatory markers.

(a). White blood cell count; (b). Lymphocyte count; (c). Neutrophils count; (d). C-reactive protein level.

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Fig 5.

Forest plot of the hospital stay length in distinct stages of patients.

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Table 1.

Subgroup and sensitivity analyses for the primary outcomes.

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Table 1 Expand