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Fig 1.

Research methodology flow chart.

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Table 1.

The antioxidant activity (DPPH, ABTS, FRAP) of jellyfish peptide after purification by reversed-phase chromatography (10–30% acetonitrile = eluent).

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Table 2.

The antioxidant activity (DPPH, ABTS, FRAP) of jellyfish peptide after purification by ion exchange chromatography (cation and anion exchange chromatography) and reverse phase chromatography (C18 column).

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Table 3.

Peptides identified from jellyfish protein hydrolysate purified by reversed-phase (C18 column) and cation exchange chromatography.

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Table 3 Expand

Fig 2.

Antioxidant activity; (A) DPPH radical scavenging activity(B) ABTS radical scavenging activity, and (C) FRAP activity of synthetic peptides.

Bars with the different letters in the same activity indicate statistically significant differences (p < 0.05).

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Fig 2 Expand

Fig 3.

ACE inhibitory activity of synthetic peptides.

Bars with the different letters indicate statistically significant differences (p < 0.05).

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Fig 3 Expand

Fig 4.

Anti-inflammatory activity of synthetic peptides.

Bars with the different letters indicate statistically significant differences (p < 0.05).

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Fig 5.

Cytotoxicity of synthetic peptides.

Bars with the different letters indicate statistically significant differences (p < 0.05). UN = untreated sample.

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Fig 5 Expand

Fig 6.

The chemical structure of MVVACVLPEA (P16).

The peptide’s 2D structure obtained using the PepDraw tool, and the peptide’s 3D structure obtained using the PEP-FOLD3 tool.

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Fig 6 Expand