Table 1.
Demographics, anthropometrics, and biochemical parameters between pre- and post-bariatric surgery (n = 19).
Fig 1.
α-diversity pre- and post-SG-surgery.
(A) Shannon; (B) Chao1; (C) Pielou’s evenness; (D) Observed OTUs; (E) Faith’s PD.
Fig 2.
Principal Coordinate Analysis (PCoA) based on (A) Unweighted UniFrac, (B) Weighted UniFrac, (C) Bray-Curtis dissimilarity, and (D) Jaccard similarity.
The total variance explained by the first two components is displayed on the PC1 and PC2 axes, respectively. Eigenvalues for the first five axes (PC1 to PC5) are provided in S3 Table. Pre-surgery (blue spheres) and post-surgery (red spheres).
Table 2.
Comparison of gut microbial composition at the phylum level pre- and post-surgery.
Fig 3.
Boxplots display the median (as the central tendency) and the interquartile range (25th to 75th percentiles) as the bottom and top edges of the box.
The whiskers extend to the most extreme data points not considered outliers (1.5 times the interquartile range), and the outliers are plotted individually. (A) LefSe discriminative analysis between pre- and obese post-surgery samples (absolute LDA score > 2). The LDA score (log10) for the more prevalent genera in the pre-surgery is represented on a positive scale (green), and the LDA score for the more prevalent genera in the post-surgery is defined on a negative scale (red). (B) Paired boxplots of Alistipes in pre- and post-surgery samples. (C) Paired boxplots of Lachnospira in pre- and post-surgery samples. (D) Paired boxplots of Saccharibacteria in pre- and post-surgery samples. (E) Paired boxplots of Lachnospiraceae UCG 004 in pre- and post-surgery samples. (F) Relative abundance of Alistipes in pre- and post-surgery samples. Means (straight line) and medians (dotted line) are shown for both groups. (G) Relative abundance of Lachnospira in pre- and post-surgery samples. Means (straight line) and medians (dotted line) are shown for both groups. (H) Relative abundance of Saccharibacteria in pre- and post-surgery samples. Means (straight line) and medians (dotted line) are shown for both groups. (I) Relative abundance of Lachnospiraceae UCG 004 in pre- and post-surgery samples. Means (straight line) and medians (dotted line) are shown for both groups.
Table 3.
Changes in gut microbial taxa (Genus level)pre- and post-surgery.