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Table 1..

Characteristics of the cohort.

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Table 1. Expand

Table 2..

The alpha diversity of the skin microbiota in each group.

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Table 2. Expand

Fig 1.

Statistical analysis of the p values of the differences in alpha diversity between groups.

Oe, elderly eczema sites; Oh, elderly health sites; OEex, elderly eczema exposed sites; OEun, elderly eczema unexposed sites; OHex, elderly healthy exposed sites; OHun, elderly healthy unexposed sites; Eo, older group eczema sites; Ey, younger group eczema sites.

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Fig 1 Expand

Fig 2.

The beta diversity of the skin microbiota between groups.

Oe, elderly eczema sites; Oh, elderly health sites; OEex, elderly eczema exposed sites; OEun, elderly eczema unexposed sites; OHex, elderly healthy exposed sites; OHun, elderly healthy unexposed sites; Eo, older group eczema sites; Ey, younger group eczema sites.

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Fig 2 Expand

Fig 3.

Comparison of the skin microbiota composition at the phylum level between groups.

A, Oe vs Oh; B, OEex vs OEun; C, OHex vs OHun; D and E: Eo vs Ey. Oe, elderly eczema sites; Oh, elderly health sites; OEex, elderly eczema exposed sites; OEun, elderly eczema unexposed sites; OHex, elderly healthy exposed sites; OHun, elderly healthy unexposed sites; Eo, older group eczema sites; Ey, younger group eczema sites.

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Fig 3 Expand

Fig 4.

Comparison of the skin microbiota composition at the genus level between groups.

A and B: Oe vs Oh; C and D: OEex vs OEun; E and F: OHex vs OHun; G and H: Eo vs Ey. Oe, elderly eczema sites; Oh, elderly health sites; OEex, elderly eczema exposed sites; OEun, elderly eczema unexposed sites; OHex, elderly healthy exposed sites; OHun, elderly healthy unexposed sites; Eo, older group eczema sites; Ey, younger group eczema sites.

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Fig 4 Expand

Fig 5.

Spearman correlation analysis.

A, The correlation between the skin microbiota at the genus level and the EASI score. B, The correlation between bacteria at the genus level.

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Fig 5 Expand

Fig 6.

Comparison of the predicted functions of the skin microbiota between groups.

A, Oe vs Oh; B, OEex vs OEun; C, Eo vs Ey, D, OHex vs OHun. Oe, elderly eczema sites; Oh, elderly health sites; OEex, elderly eczema exposed sites; OEun, elderly eczema unexposed sites; OHex, elderly healthy exposed sites; OHun, elderly healthy unexposed sites; Eo, older group eczema sites; Ey, younger group eczema sites.

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Fig 6 Expand