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Fig 1.

PRISMA flowchart of the article selection process.

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Table 1.

Basic characteristics of the studies included.

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Fig 2.

Forest plot showing the odds of 5-year overall-survival rate among children with brain tumors treated with either PT or XRT.

OR: odds ratio, CI: confidence interval. Events means survival.

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Fig 3.

Forest plot showing the ratio of odds of hypothyroidism (=event) among pediatric brain cancer patients treated with either PT or XRT.

OR: odds ratio (proton/photon), CI: confidence interval.

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Fig 4.

Forest plot showing the mean difference of global IQ level among pediatric brain cancer patients treated with either PT or XRT.

MD: mean difference, CI: confidence interval.

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Fig 5.

Forest plot showing the ratio of odds of acute side effects: nausea (a) and vomiting (b) (=events) among pediatric patients with brain tumors treated with PT or XRT.

OR: odds ratio (proton/photon), CI: confidence interval.

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Fig 6.

Forest plot showing the ratio of odds of grade 3 anemia (=event) among pediatric patients with brain tumors treated with either PT or XRT.

OR: odds ratio (proton/photon), CI: confidence interval.

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