Fig 1.
An overall scheme of the individualization process of mechanical ventilation setting.
ICU: Intensive care unit. PEEP: Positive end-expiratory pressure. VE: Minute ventilation. MP: Mechanical power. TV: Tidal volume.
Fig 2.
Patient inclusion flow chart.
Table 1.
Characteristics of patients admitted to the ICUBSA, Body Service Area; ICU, Intensive Care Unit.
Table 2.
Laboratory values of the study population during admission.
Table 3.
Mechanical ventilation measurements in the first 24 and 48 hours of admission.
Table 4.
Mechanical power according to hypoxemia status and mortality.
Fig 3.
COX-survival curve according to the found safe limits of 48 h-TWA, IBW-adjusted MP.
Stratified into hypoxemic levels: nonhypoxemic (top left), mildly hypoxemic (top right), moderately hypoxemic (bottom left), and severely hypoxemic (bottom right). TWA: Time-weighted average. IBW: Ideal body weight. MP: Mechanical power.
Fig 4.
SHAP values display the sensitivity of the XGBoost model in predicting ICU mortality against different covariables.
TWA: Time Weighted Average. APPT: Activated Partial Thromboplastin Clotting Time. ASAT: Aspartate Aminotransferase. MP: Mechanical power. IBW: Ideal Body Weight. PEEP: Positive End Expiratory Pressure.
Table 5.
Prediction performance of each model.