Fig 1.
Participants flow chart.
Fig 2.
Directed acyclic graph of the assumed associations between dialysis modality before transplantation, adherence to immunosuppression medication after kidney transplantation and background factors.
Table 1.
Results are expressed as means (95% CI) unless otherwise indicated.
Statistically significant differences are shown in bold. Pre-emptive Tx is omitted in this table (N = 1). HRQoL was measured with a 15D instrument. DM: diabetes mellitus. CGN: chronic glomerulonephritis. ADPKD: autosomal dominant polycystic kidney disease. CIN: chronic interstitial nephritis. CKD: chronic kidney disease. RRS: recipient risk score for comorbidities.
Table 2.
Multimethod assessment of adherence split by previous dialysis modality.
BAASIS- questionnaire results split by previous dialysis modality. VAS: visual analogue scale. COV: coefficient of variance; CNI: calcineurin inhibitor; MRCI: medication regimen complexity index. COV-CNI, pills, meds, and MRCI are values expressed in mean (95%CI) The rest of the results are in %. Subgroups with statistically significant differences are in bold.
Table 3.
Q-sort statements are grouped according to personality type.
The statements that statistically significantly distinguish all the profiles in different directions are shown in bold.
Fig 3.
Distinction of the patient´s profiles based on six statements.
Table 4.
Differences between the three profiles were defined by Q-analysis.
Results are expressed as means (95% CI). COV-CNI: coefficient of variance of calcineurin inhibitors. RRS: recipient risk score (i.e. comorbidity score). HRQoL: health-related quality of life. MRCI: medication regimen complexity index. *HHD, CAPD, APD, ICHD. Statistically significant differences are shown in bold.
Fig 4.
Fully adherent means never missing a dose and always taking the medication on time.
Fig 5.
Death-censored graft survival (DCGS) curve in considering taking (upper panel), timing (middle panel), and patient attitudes to transplantation (lower panel) revealed by factor analysis showing the associations of the three profiles with DCGS.
Table 5.
Outcome: death censored graft survival. Statistically significant confounders are in bold. HR: hazard ratio. Timing: always versus never on time. Missing: never (ref) versus sometimes. Timing: always on time (ref) vs never on time. Age: at participation. AR: previous acute rejection (no is the ref). Factor: Q-sort factor analysis group.