Fig 1.
Calibration curve of Framycetin Sulphate.
Table 1.
Composition of FC-S-loaded hydrogel dressing.
Table 2.
Entrapment efficiency.
Fig 2.
Fourier transform infrared (FTIR) spectra of framycetin sulphate (A) and drug- loaded hydrogel dressing (B).
Fig 3.
Equilibrium Swelling ratio of Polyvinyl alcohol/Polyvinyl pyrrolidone/Sodium alginate hydrogel dressing loaded with Framycetin Sulphate 1.FH5, 2.FH9, 3.FH11, 4.FH12.
Table 3.
Percentage equilibrium swelling ratio SR data of FC-S loaded hydrogel dressing.
Fig 4.
Dynamic swelling ratio (%) of Framycetin sulphate loaded hydrogel dressing of FH 5, FH9, FH11, FH12.
Table 4.
Dynamic swelling ratio % of FC-S loaded hydrogel dressing.
Fig 5.
Drug release profile of FH5, FH9, FH11, FH12.
Fig 6.
The images representing the wound on rat model (A) Treated with Framycetin Sulphate loaded hydrogel dressing (B) Non treated rat wound (C) Rat wound treated with commercial product Sufre Tulle gauze (D) Drug free hydrogel dressing treated rat wound.
The framycetin sulphate loaded hydrogel dressing were composed of Framycetin sulphate drug polyvinyl alcohol, polyvinylpyrrolidone,sodiumalginate.
Table 5.
Drug release pattern of FC-S-loaded hydrogels FH 5, FH 9, FH11, FH 12 by employing different kinetics model.
Table 6.
Release exponent (n) and order of release of FC-S-loaded hydrogel dressing.
Table 7.
Drug release data of FC-S loaded hydrogel-dressing sample FH 5, FH 9, FH 11, FH 12.
Table 8.
Wound size reduction in rat treated with FC-S hydrogels, nontreated, commercial product and drug free hydrogels.
Table 9.
Percentage wound healing on rats model ingroups A, B, C and D.
Fig 7.
Wound curing profile of rats (wound model) Treated with framycetin sulphate loaded hydrogel dressing treated rat, Non treated rat wound, rat wound treated with commercial product Suffre Tulle gauze, Drug free hydrogel dressing treated rat wound.
The framycetin sulphate loaded hydrogel dressing were composed of framycetin sulphate drug/Polyvinyl alcohol/Polyvinyl pyrrolidone/Sodium alginate ratio.
Fig 8.
Scanning electron microscopic images of unloaded hydrogels (A) and loaded (B) dressingsdressings.