Fig 1.
Schematic figure summarizing the experimental design.
Fig 2.
SBP, systolic blood pressure; HIIT, high intensity interval training; x, times repeated; %, percentage.
Table 1.
Initial and final systolic blood pressure.
Fig 3.
Gene expression of NADPH oxidase complex (a-d) and NF-kB pathway (e-f) in TA muscles. SHRC: control hypertensive (n = 9), SHR+T: trained hypertensive (n = 10), a.u.: arbitrary unit. Data expressed as mean ± standard deviation (t test) or median, minimum, and maximum. (Mann Whitney test).
Fig 4.
Oxidative stress in TA muscles.
(a) MDA: malonaldehyde, (b) protein carbonylation, (c) HAC: hydrophilic antioxidant capacity. SHRC: control hypertensive (n = 9), SHR+T: trained hypertensive (n = 10). Data expressed as mean ± standard deviation. t test, *p < 0.05 compared to SHRC.
Fig 5.
Cytokine levels in TA muscles.
(a) IL-6: interleukin-6, (b) TNF-α: tumor necrosis factor-alpha. SHRC: control hypertensive (n = 9), SHR+T: trained hypertensive (n = 10). Data expressed as mean ± standard deviation, t test, * p < 0.05 compared to SHRC.
Fig 6.
Schematic representation of the skeletal muscle adaptations to HIIT in rats with chronic hypertension.
Emphasis on the impact of HIIT on muscle oxidative stress and inflammatory markers, highlighting its potential therapeutic implications for cardiovascular health.