Fig 1.
Data representative for physico-chemical characteristics of thyme oil nanoparticles.
a) hydrodynamic diameter measurement of TO-SLN by DLS. b) zeta potential of TO-SLN. c) hydrodynamic diameter measurement of TO-CH using DLS. d) zeta potential of TO-CH.
Table 1.
Average size, zeta potential, PDI, and entrapment efficiency of thyme oil loaded solid lipid nanoparticles (TO-SLN) and thyme oil loaded chitosan nanoparticles (TO-CH).
Fig 2.
TEM two-dimensional structural qualification.
a) TO-SLN on the scale of 60 nm, b) TO-CH on the scale of 250 nm.
Fig 3.
ATR-FTIR spectra of thyme oil (blue), TO-SLN (green) and TO-CH (red).
Fig 4.
Data represents the cumulative release profile of thyme oil from TO-SLN and TO-CH in 72 h.
Fig 5.
The cell viability% treated with thyme oil (mg mL-1) compared with thyme oil loaded SLN and chitosan nanoparticles (5 mg mL-1).
Table 2.
The MIC and MBC values (μg mL-1) for pure thyme oil, thyme oil loaded solid lipid nanoparticles (TO-SLN) and thyme oil loaded chitosan nanoparticles (TO-CH) against S. typhimurium and E. coli.
Fig 6.
Variation of S. typhimurium viability in presence of TO, TO-SLN and TO-CH with the concentrations of MIC, ½ MIC and ¼ MIC in days 0,2,4 and 6.