Fig 1.
Estimations of incidence (A) and prevalence (B) of FSGS among US veterans.
Abbreviations: FSGS, focal segmental glomerulosclerosis; US, United States. Data source: Source: US Veteran Affairs Health System Corporate Data Warehouse (October 1999–February 2021).
Table 1.
Demographic, clinical, and disease characteristics: United States, 2000–2020.
Table 2.
Clinical events during the follow-up perioda.
Fig 2.
Overall survival analysis from the index date.
Abbreviations: CI, confidence interval; FSGS, focal segmental glomerulosclerosis; KM, Kaplan-Meier. Note: a Survival was measured as the number of days between the index date (date of first diagnosis of FSGS) and the date of death from any cause. Patients who did not experience the event were censored at the end of the follow-up period.
Fig 3.
Kaplan Meier curves of time to (A) first KF or deatha, (B) first dialysisb, and (C) first renal transplant from the index datec.
Abbreviations: CI, confidence interval; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; FSGS, focal segmental glomerulosclerosis; KF, kidney failure; KM, Kaplan-Meier; NR, not reached. Notes: a Time to first KF or death was measured as the number of days between the index date (date of first diagnosis of FSGS) and the date of first KF event or death during the follow up period. Patients who did not experience the event were censored at the end of the follow-up period. An event was defined as a composite measure including KF identified via diagnosis codes (585.6x and N18.6x), CKD stage 5 (eGFR<15 mL/min/1.73 m2 or diagnosis code [585.5x and N18.5]), kidney transplant, dialysis, and death. b Measured as the number of days between the index date and the date of the first dialysis event during the follow up period. Patients who did not experience the event were censored at the end of the follow-up period. c Measured as the number of days between the index date and date of first renal transplant event during follow up period. Patients who did not experience the event were censored at the end of the follow-up period.
Table 3.
Time to first KF or death, first dialysis, and first renal transplant during the follow-up perioda.
Table 4.
HRU and healthcare costs during the follow-up perioda.