Fig 1.
Flowchart for cohort selection from the HealthLNK database.
Fig 2.
Diagram of the pathophysiological representation of cirrhosis trajectory.
HE: hepatic Encephalopathy, HPS: hepatopulmonary Syndrome, HRS: hepatorenal syndrome, SBP: spontaneous bacterial peritonitis, TIPS: transjugular intrahepatic portosystemic shunt.
Table 1.
Demographics and 1-year outcomes of patients with cirrhosis stratified by initial stage.
Fig 3.
1-year Cirrhosis Progression Stages diagram.
Progression of cirrhosis over 1-year follow-up from index cirrhosis diagnosis based on the Baveno VII consensus stages of cirrhosis. Proportion of patients that advance from each stage towards higher stage, transplant, or death.
Fig 4.
Cumulative incidence graph of competing risk analysis for mortality, stage progression and/or transplant.
Cumulative incidence graphs of competing risk analysis with liver transplantation, non-liver related death, and liver-related death as the competing risks of interest. Patients in Stages 1–4 also had the proceeding higher stages as additional competing risks events. At all stages, even in patients with decompensating complications, patients had higher rates of mortality than LT. LT: liver transplant, Stage 1: without portal hypertension, Stage 2: with portal hypertension, Stage 3: bleeding, Stage 4: non-bleeding decompensation complication, Stage 5: ≥2 different decompensation complications.
Table 2.
Competing risk analysis of patients with cirrhosis identifying predictors of all-cause mortality and liver-related death.