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Fig 1.

Study schema for MTN-030/IPM 041.

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Fig 2.

Study schema for MTN-044/IPM 053/CCN019.

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Fig 3.

Framework for evaluating acceptability in microbicide and PrEP trials [37].

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Table 1.

Baseline characteristics by study and study arm (MTN-030/IPM 041 [n = 23] and MTN-044/IPM 053/CCN019 [n = 25]).

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Table 1 Expand

Table 2.

Acceptability by study (MTN-030/IPM 041 [n = 23] and MTN-044/IPM 053/CCN019 [n = 25]) and by study arm.

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Table 2 Expand

Fig 4.

Heatmap of bleeding patterns, MTN-030/IPM 041 (n = 23).

green = no bleeding, yellow = light bleeding, pink = moderate bleeding, red = heavy bleeding.

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Fig 4 Expand

Table 3.

Adherence (expulsions and removals) and bleeding incidence by study (MTN-030/IPM 041 [n = 23] and MTN-044/IPM 053/CCN019 [n = 25]) and by study arm.

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Table 3 Expand

Fig 5.

Heatmap of bleeding patterns, MTN-044/IPM 053/CCN019 (n = 25).

green = no bleeding, yellow = light bleeding, pink = moderate bleeding, red = heavy bleeding.

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Fig 5 Expand

Table 4.

Impact of product characteristics, adherence, and bleeding patterns on overall acceptability, by study (MTN-030/IPM 041 [n = 23] and MTN-044/IPM 053/CCN019 [n = 25]).

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