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Fig 1.

Representative images of early gastric cancer with mean visibility score of 1.0, 3.0, 5.0 on WLI.

(a) Type 0-IIb early gastric cancer located on posterior wall of gastric angle (yellow triangle). Mean visibility score of this lesion was 1.0. (b) Type 0-IIc early gastric cancer located on lesser curvature of the upper gastric body (yellow triangle). Mean visibility score of this lesion was 3.0. (c) Type 0-IIc early gastric cancer located on greater curvature of gastric antrum (yellow triangle). Mean visibility score of this lesion was 5.0.

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Fig 1 Expand

Fig 2.

Study flowchart.

Good visibility, lesions with mean visibility score ≥3 on WLI; poor visibility, lesions with mean visibility score <3 on WLI.

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Fig 2 Expand

Table 1.

Baseline characteristics of patients and early gastric cancer and background gastric mucosa.

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Table 1 Expand

Table 2.

Univariate and multivariate analysis of factors associated with visibility of early gastric cancer on WLI.

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Table 2 Expand

Fig 3.

Comparison of mean visibility score between WLI and LCI. WLI, White light imaging; LCI, Linked color imaging; *, statistically significant.

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Fig 3 Expand

Fig 4.

Representative images of early gastric cancer in which the visibility was classified as poor visibility on WLI but improved to good visibility on LCI.

Type 0-Ⅱc early gastric cancer, 9 mm in size, located on posterior wall of the upper gastric body (yellow triangle). The mean visibility score on WLI was 1.7, which was classified as poor visibility (a), but the mean visibility score on LCI improved to 3.0 (b). WLI, White light imaging; LCI, Linked color imaging.

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Fig 4 Expand

Fig 5.

Comparison of mean visibility score of WLI and LCI in good visibility lesions and poor visibility lesions.

WLI, White light imaging; LCI, Linked color imaging; good visibility, lesions with mean visibility score ≥3 on WLI; poor visibility, lesions with mean visibility score <3 on WLI; *, statistically significant.

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Fig 5 Expand

Fig 6.

Comparison of visibility score of WLI and LCI by presence or absence of intestinal metaplasia and lesion size.

(a), (b) Comparison of visibility score of WLI and LCI by presence or absence of intestinal metaplasia, (c), (d), (e) Comparison of visibility score of WLI and LCI by lesion size. WLI, White light imaging; LCI, Linked color imaging; IM-, lesions without endoscopic intestinal metaplasia; IM+, lesions with mild or sever endoscopic intestinal metaplasia; *, statistically significant.

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Fig 6 Expand