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Fig 1.

General DR lesions observed in the fundus images.

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Fig 2.

Stages of development of diabetic retinopathy.

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Fig 3.

Proposed research methodology for DR diagnosis.

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Fig 4.

(a) Retinal Lesions in Fundus Images, (b) hard exudates, (c) soft exudates, (d) haemorrhages, and (e) microaneurysms.

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Fig 5.

GauGAN architecture.

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Fig 6.

KCBGWO flowchart.

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Fig 7.

FCEDN architecture.

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Fig 8.

Overview of feature extraction with fusion approaches and the FuNet model.

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Fig 9.

ELM configuration.

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Table 1.

Mathematical representation of performance evaluation matrices.

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Table 2.

Hyperparameters and performance metrics of BGWO with K-means clustering.

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Table 3.

Optimization algorithms performance comparison across benchmark functions.

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Fig 10.

Detailed portrayal of the diabetic retinopathy identification workflow.

(a) Initial retinal image, (b) Enhanced image post-preprocessing, (c) Identification of red lesions (RL), (d) Identification of bright lesions (BL), (e) Quantitative feature labels on bright lesions, and (f) Quantitative feature labels on red lesions.

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Fig 11.

Feature extraction-based classification results using pre-trained CNN models.

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Table 4.

Classification outcomes utilizing feature extraction from diverse pre-trained CNN models and various down sampling approaches.

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Fig 12.

AUC for each stage.

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Table 5.

IDRiD-based state-of-the-art comparison.

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