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Fig 1.

Composition of the groups evaluated in order to analyze the temporal criterion for determining the timing of kidney replacement therapy (KRT).

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Fig 2.

Flowchart of the patient selection process.

SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; CKD, chronic kidney disease, COVID-19, coronavirus disease 2019; AKI, acute kidney injury; ICU, intensive care unit.

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Table 1.

Characteristics of patients with coronavirus disease 2019-related acute kidney injury, by the timing of kidney replacement therapy, as determined on the basis of a temporal criterion.

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Table 2.

Logistic regression analyses of the association between the timing of kidney replacement therapy, as determined on the basis of a temporal criterion, and in-hospital mortality among patients with coronavirus disease 2019-related acute kidney injury.

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Table 2 Expand

Table 3.

Logistic regression analyses of the association between the timing of kidney replacement therapy, as determined on the basis of a serum creatinine cutoff criterion, and in-hospital mortality among patients with coronavirus disease 2019-related acute kidney injury.

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Fig 3.

Restricted cubic spline model depicting the unadjusted relationship (with 95% confidence intervals) between the timing of kidney replacement therapy (KRT), as determined on the basis of a temporal criterion, and the predicted probability of in-hospital mortality in patients with coronavirus disease 2019-related acute kidney injury.

Vertical lines show the spike histogram. The dashed vertical line indicates the median days from admission to KRT initiation in the sample as a whole.

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Table 4.

Receiver operating characteristic curve analyses of the performance of timing of kidney replacement therapy for the prediction of in-hospital mortality among patients with coronavirus disease 2019-related acute kidney injury.

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