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Fig 1.

The EpiMAP myeloma model framework.

Blue health states represent treatments where best clinical response is predicted, either to chemotherapy or autologous stem cell transplant. Grey health states represent treatment-free intervals or post-induction maintenance therapy.

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Table 1.

Patient characteristics at diagnosis.

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Table 1 Expand

Fig 2.

95% confidence intervals of the Kaplan-Meier OS curves for the validation and simulated cohorts.

The dashed light blue line represents the monthly p-value evaluating the significance of the difference between the confidence intervals.

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Fig 2 Expand

Table 2.

Overall survival by BCR to LoT 1 / ASCT.

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Table 2 Expand

Fig 3.

Overall survival curves by BCR to LoT 1 / ASCT for the simulated cohort.

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Fig 3 Expand