Fig 1.
Diagnostic performance of the BIMAST score for predicting significant and advanced fibrosis in the derivation cohort (diabetes primary care).
The figure illustrates the receiver operating characteristic curve of the BIMAST score for predicting LSM ≥ 8.1 kPa (Fig 1A) and for predicting LSM ≥ 12.1 kPa (Fig 1B) in the derivation cohort (diabetes primary care).
Table 1.
Diagnostic performance of the BIMAST in the derivation and validation cohorts.
Fig 2.
BIMAST score vs conventional screening methods for predicting significant and advanced fibrosis in the diabetic primary care population (whole study population).
The figure illustrates the receiver operating characteristic curve of the BIMAST score vs conventional methods for predicting LSM ≥ 8.1 kPa (Fig 2A) and for predicting LSM ≥ 12.1 kPa (Fig 2B) in the whole study population.
Fig 3.
BIMAST score vs FIB-4 for predicting significant and advanced fibrosis in the Royal Free cohort.
The figure shows the receiver operating characteristic curve of BIMAST score vs FIB-4 for predicting LSM≥ 8.1 kPa (Fig 3A) and LSM ≥12.1 kPa (Fig 3B) in the Royal Free cohort.
Fig 4.
BIMAST score vs FIB-4 for predicting significant and advanced fibrosis in the Sicilian cohort.
The figure shows the receiver operating characteristic curve of BIMAST score vs FIB-4 for predicting LSM≥ 8.1 kPa (Fig 4A) and LSM ≥12.1 kPa (Fig 4B) in the Sicilian cohort.
Table 2.
Base-case cost-effectiveness analysis of MASLD screening strategies versus standard of care (baseline screening).
Fig 5.
Cost-effectiveness acceptability curve (strategy 1 to 6).
Red and blue lines represent the cost-effectiveness acceptability of the screening strategy and SOC, respectively. Each dot on the graph shows the probability of strategy 4 being cost-effective (Y-axis) at a given cost-effectiveness threshold (X-axis). 1. point A shows the point at which both strategies have 50% probability of being cost-effective; 2. point B shows the point at which scenario 1 has 100% probability of being cost-effective. SOC: standard of care.