Fig 1.
Flowchart of participant recruitment.
POD = Postoperative Delirium, OCT = Optical Coherence Tomography.
Fig 2.
HH-OCT circumpapillary retinal nerve fibre layer thickness measurement in a participant.
The cpRNFL thickness was divided into 10 radial segments (using the GDx Nerve Fiber Analyzer protocol, Carl Zeiss Meditec). The quadrants are created by amalgamating two (temporal), two (nasal), three (superior) and three (inferior) radial segments. The colours represent comparison to age-adjusted normative values (green = normal, yellow = borderline and red = out of range).
Table 1.
Recruitment pattern and demographics of participants and excluded people.
Table 2.
Baseline characteristics of participants.
Fig 3.
Box plot of Mean cpRNFL (μm) at Ring diameter 2.83mm in participants who did not have postoperative delirium and participants who had postoperative delirium with individual participant’s values.
POD = postoperative delirium, RNFL = retinal nerve fibre layer.
Fig 4.
Boxplot of cpRNFL thickness (μm) by Quadrants at ring diameter 2.83mm comparing participants who had postoperative delirium to those who did not experience postoperative delirium.
POD = Postoperative delirium, RNFL = Retinal Nerve Fibre Layer.
Table 3.
Exploratory analysis of mean and segmental circumpapillary retinal nerve fibre thickness between participants who did not have postoperative delirium and those who had postoperative delirium (Descriptive statistics and Mann-Whitney U statistic).
Table 4.
Reasons for exclusion.