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Fig 1.

Overview of the study design and participants included from baseline to 5-year follow-up.

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Table 1.

Descriptive characteristics of the study population at baseline.

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Table 2.

Comparison of baseline to follow-up data in the ART-treated, ART-naïve and control groups (initial group).

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Table 2 Expand

Fig 2.

The between-group difference in the degree of change over time for lag time.

(A) presents the unadjusted model, (B) is Model 1, which adjusted for covariates that demonstrated differences in changes between the three groups, whilst (C) is for Model 2, which additionally adjusted for fibrinogen concentration. The interaction p-value represents the statistical significance of the differences.

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Table 3.

Comparison of baseline and follow-up data in ART-treated, ART-naïve and control groups (sub-group).

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Table 3 Expand

Fig 3.

The between-group differences in the degree of change over the 5-year period for permeability in the sub-group.

The interaction p-value represents the statistical significance of the differences.

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Fig 3 Expand