Table 1.
Age at first reliable examination among patients in different groups.
Fig 1.
Flow chart of study population.
NF1—neurofibromatosis type 1, OPG—optic pathway glioma, S-sporadic.
Table 2.
Comparison of estimated values of four parameters (VA, VFI, GC-IPL and pRNFL) among three groups of eyes.
Fig 2.
A model of change in four main parameters during a three-year study period in the groups.
A) VA, B) GC-IPL, C) pRNFL, D) VFI. NF1—neurofibromatosis type 1, OPG—optic pathway glioma, VA- visual acuity, GC-IPL—ganglion cell—inner plexiform layer, pRNFL- peripapillary retinal nerve fiber layer, S—sporadic, VFI- Visual Field Index.
Fig 3.
Graphs present longitudinal VA and GC-IPL measurements obtained during the study period.
CF: count fingers (LogMAR = 2.0); GC-IPL: ganglion cell inner plexiform layer; HM: hand movement (LogMAR = 2.5); LE: left eye; LP: light perception (LogMAR = 3.0); NF1: neurofibromatosis type 1; NLP: no light perception (LogMAR = 3.5); RE: right eye; S: sporadic optic pathway glioma. Different anatomic locations of optic pathway gliomas. Extension of tumors: (1) intraconal (posterior boundary orbital apex); (2) intracanalicular (posterior boundary optic foramen); (3) intra‐cranial‐prechiasmatic; (4) chiasmatic; (5) optic tract; (6) lateral geniculate nucleus; (7) optic radiation; B: both left och right, L: left; R = right.