Fig 1.
Schedule of procedures testing the applicability and safety of using self-capillary blood collection.
Table 1.
Characteristics of participants.
Fig 2.
Distribution of blood volume and pain perception in the adult investigational phase.
The box plots show the distribution of median capillary blood volume (in μl) in A and of the pain level on the 11-point Louisiane pain scale in B, displayed by puncture site (upper arm or lower back) and use of topical analgesia (use in dark or no in clear boxes). The median volume is depicted in each box. The mean group difference with 95% CI within the puncture sites, between topical analgesia use or not, is displayed on top of the box plots.
Fig 3.
Feedback from participants on training, satisfaction and preference with the capillary sampling device.
Questionnaire responses of participants enrolled in the adult investigation phase are displayed in Panel A, and those of children and their parent enrolled in the child-parent dyad in Panel B. A bar chart is provided for each question on the y-axis regarding the instructional materials, live guidance, experience and preference. The proportion of participants with agreement (i.e., answered 4 or 5 on the 5-point Likert scale) is displayed on the right of the identity line. In contrast, neutral responses are straddling, and disagreement is shown on the left of the identity line.
Fig 4.
Distribution of capillary blood volume per device across all phases.
The box plots show the distribution of median capillary blood volume (in μl) per device in the adult and child-parent dyad study during the investigational phase and in the PROTECT and DIVA studies during the implementation phase. Horizontal lines within each box plot represent the median.
Table 2.
Adverse health events.