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Fig 1.

SPIRIT schedule of enrolment, interventions, and assessments.

Abbreviations: hCG = human chorionic gonadotropin; AE = adverse events; SAE = severe adverse events. 1 All subjects will be observed by the Investigator or qualified designee for at least 30 minutes after each study vaccination for any untoward effects, including allergic reactions.

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Fig 2.

Infectivity assay performed on HaCaT cells before and after vaccination with Gardasil-9.

Created with BioRender.com.

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