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Fig 1.

The small volume “flex” metabolic chamber at the Fralin Biomedical Research Institute at Virginia Tech Carilion in Roanoke, Virginia, set up for a resting measurement.

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Fig 2.

A sample infusion depicting expected (solid) and observed (dashed) (A) VO2 and (B) VCO2 values. Resting, stepped increase, and human study simulation event sections are denoted by differing background shading.

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Table 1.

Reproducibility of O2 and CO2 recovery across specified event sections during infusion validation studies (n = 3).

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Table 2.

Participant characteristics (n = 16).

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Table 2 Expand

Fig 3.

Mean resting (A) metabolic rate, (B) carbohydrate oxidation, and (C) respiratory exchange ratio across dextrose (n = 13), fructose (n = 16), and sucrose (n = 13) conditions assessed by linear mixed effects models.

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Fig 4.

Postprandial change from resting (A) metabolic rate, (C) carbohydrate oxidation, and (E) RER; and areas under the curve for percent change from resting (B) metabolic rate, (D) carbohydrate oxidation, and (F) RER in response to consumption of 75-kcal beverages containing dextrose, fructose, or sucrose. Gray background on line plots A, C, and E indicate data 4 minutes before and after drink consumption, which were excluded from analysis. Data are expressed as mean ± standard error of the mean. *, p<0.05; RER: respiratory exchange ratio.

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Table 3.

Comparison postprandial carbohydrate oxidation parameters in response to dextrose-, fructose-, and sucrose-containing beverage consumption as assessed by standard methods and Bayesian Hierarchical Modeling statistical methods.

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Table 3 Expand