Fig 1.
Measurement of body composition via dual x-ray absorptiometry (DEXA).
A rectangle was drawn on the digital image bounded superiorly by a horizontal line identifying the T12/L1 intervertebral space, inferiorly by a horizontal line denoting the L4/L5 intervertebral space, and bilaterally by connecting the two horizontal lines in a region free of tissue. Abdominal adiposity, DXA L1-L4, was defined as the fat mass within this region.
Table 1.
Baseline characteristics of participants (N = 92).
Table 2.
Multivariable regression model on homeostatic model assessment of insulin resistance (HOMA-IR, log scale).
Fig 2.
Adjusted association between insulin resistance (HOMA-IR) and appendicular lean mass by BMI category.
Fig 3.
Schematic of potential pathophysiology between body composition and insulin resistance.
Aging is associated with increased fat mass and decreased muscle mass. Fat mass may be related to muscle due to lipid deposition whereas muscle may be related to insulin resistance through muscle heterogeneity.