Fig 1.
Flow diagram of the selection of the study population from the National Health Information Database.
a Patients aged ≥20 years and <40 years who participated in the National Health Insurance Service at least once between 2009 and 2012. b Patients who received a health examination between January 1, 2009, and December 31, 2012 and have subsequently undergone four consecutive examinations thereafter (For example, for 2009, participants who underwent annual health examinations continuously for four years from 2009 to 2012). c Patients diagnosed with retinal vein occlusion (KCD code H34.8 corresponding to ICD-10-clinical modification code 362.35, CRVO, or 362.36, venous tributary (branch) occlusion) during the washout period were excluded. d Patients diagnosed with retinal vein occlusion within one year from the index date were excluded (For example, for 2009, individuals who received annual health examinations from 2009 to 2012 and experienced RVO or passed away in 2013 were excluded). CRVO central retinal vein occlusion.
Table 1.
Baseline characteristics of the total study population according to the cumulative number of MetS diagnosed at each health examination (0 to 4 times).
Fig 2.
Incidence rate of retinal vein occlusion according to the a. cumulative number of MetS diagnosed at each health examination, and b-f. cumulative number of each component of MetS diagnosed at each health examination. HDL high‑density lipoprotein, TG triglycerides.
Table 2.
The risk of retinal vein occlusion according to the cumulative number of MetS and each component diagnosed during four health examinations (0 to 4 times).
Table 3.
The risk of retinal vein occlusion according to the cumulative number of MetS in various subgroups.