Fig 1.
Flow of included patients through the trial.
Abbreviations: MIMIC-IV, the medical information mart for intensive care IV; RDW: red cell distribution width.
Table 1.
Baseline characteristics of critical patients with BC grouped according to RDW index quartiles.
Table 2.
Baseline characteristics of the survivors and non-survivors groups.
Fig 2.
Kaplan–Meier survival analysis curves for all-cause mortality.
Footnote RDW index quartiles: Q1 (10.8–13.4), Q2 (13.4–14.6), Q3 (14.6–16.4), Q4 (16.4–26.8). Kaplan–Meier curves showing a cumulative probability of all-cause mortality according to groups at 6 months (a), 1 year (b), and 3 years (c).
Fig 3.
Hazard ratios (95% CIs) for hospital mortality according to RDW index quartiles of model 3.
Hazard ratios (95% CIs) for 6-month (a), 1-year (b), and 3-year (c) mortality according to RDW index quartiles after adjusting for age, race, BMI, radiation, medication, breast surgery, MI, CHF, peripheral vascular disease, cerebrovascular disease, chronic pulmonary disease, rheumatic disease, mild liver disease, diabetes without cc, diabetes with cc, renal disease, severe liver disease, metastatic solid tumor. Error bars indicate 95% CIs. The first quartile is the reference. CI, confidence interval. Abbreviations: RDW, red cell distribution width.
Table 3.
Cox proportional hazard ratios (HR) for all-cause mortality.
Fig 4.
Restricted cubic spline curves for the RDW hazard ratio.
Heavy central lines represent the estimated adjusted hazard ratios, with shaded ribbons denoting 95% confidence intervals. RDW index 14.6 was selected as the reference level represented by the vertical dotted lines. The horizontal dotted lines represent the hazard ratio of 1.0. (a) Restricted cubic spline for 6-month mortality. (b) Restricted cubic spline for 1-year mortality. (c) Restricted cubic spline for 3-year mortality. HR, hazard ratio; CI, confidence interval. Abbreviations: RDW, red cell distribution width.
Table 4.
Multivariate Cox analyses for categorized RDW and clinical outcomes in BC patients in different subgroups according to the fully adjusted model (Model 3).