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Fig 1.

Map pointing of the study sites created in the MapChart website [22] and modified accordingly.

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Fig 1 Expand

Fig 2.

Schematic workflow of the field studies in Malinau and Nunukan Regencies, and Jakarta, Indonesia.

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Fig 3.

Test interpretation of the One-Step G6PD test.

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Fig 4.

Histogram of G6PD activity as measured by spectrophotometry of female and male participants from Indonesia (n = 158).

Vertical red lines denote (from left to right) 30%, 70% and 100% of AMM. Sex was not recorded in 3 participants.

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Fig 4 Expand

Table 1.

Demography and G6PD activity of the study populations.

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Table 1 Expand

Table 2.

Summary of genotyping results of male participants with deficient G6PD activity and female participants with deficient and intermediate G6PD activity.

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Table 2 Expand

Table 3.

Performance of the RDT against reference spectrophotometry.

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Table 3 Expand

Table 4.

PPV and NPV for different G6PD deficiency prevalence based on the performance of the RDT in identifying deficient and deficient / intermediate individuals (Table 3).

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Table 4 Expand