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Table 1.

Eligibility criteria based on the PECo strategy.

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Table 2.

Risk of bias assessment.

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Fig 1.

PRISMA flow diagram.

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Fig 2.

Trend of publications.

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Table 3.

Types of CADD methods used and the study context.

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Table 4.

Summary of different docking tools used in the studies.

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Table 5.

Molecular dynamic simulation software used.

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Table 6.

Online ligand databases used.

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Fig 3.

Chemical structure depiction of the hit compounds.

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Table 7.

Target proteins and anticancer properties of anthraquinone derivatives elucidated by CADD methods.

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Table 7 Expand

Fig 4.

Targets involved that tackled the hallmarks of cancer.

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Fig 5.

Risk of bias assessment outcome.

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