Fig 1.
A) Modified odor identification cards, each one has a cover to prevent odor cross-contamination. All nine folded odor identification cards were mailed together inside a small plastic bag B) Screenshot of the online platform showing the four possible answers for odor 1.
Fig 2.
Odor identification attributed to each odor card.
The correct response is at the header of each panel. Legend in each figure indicates the 4 options from which the participant had to choose, one was the correct answer and the other 3 were the distractors.
Table 1.
Participants’ demographic information.
The population ranged from 40 to 90 years old. A total of 1,163 participants completed this study.
Table 2.
Comparison of correct responses obtained performing the test via self-administration or with a tester administering the test.
A) Percentage of individuals younger than 65 that correctly identified the odorant. B) Percentage of individuals older than 65 that correctly identified the odorant. Significance determined by Tukey unequal n posthoc.
Fig 3.
Comparison of the self-administered vs tester-administered NIH Toolbox test.
Mean proportion correct score for the self-administered test (solid line) compared to the tester-administered test (dashed line). Age-dependent olfactory decline can be detected using the NIH odor identification cards. For the self-administered group 40-49 n = 38, 50-59 n = 300, 60-69 n = 537, 70-79 n = 266, 80-85 n = 20. For the tester-administered group 40-49 n = 256, 50-59 n = 192, 60-69 n = 158, 70-79 n = 143, 80-85 n = 96. ***Significance p<0.001.