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Table 1.

Characteristics of male and female participants at Exam 1, Exam 2 and Exam 3.

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Table 1 Expand

Fig 1.

Risk factor trajectories according to cluster membership of men.

Presented are mean risk factor levels at each examination according to cluster membership. Clusters are based on male participants’ longitudinal risk profile trajectories determined by k-means clustering.

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Fig 1 Expand

Fig 2.

Risk factor trajectories according to cluster membership of women.

Presented are mean risk factor levels at each examination according to cluster membership. Clusters are based on female participants’ longitudinal risk profile trajectories determined by k-means clustering.

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Fig 2 Expand

Fig 3.

Distribution of prevalent and incident cardiometabolic cases according to cluster.

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Fig 3 Expand

Fig 4.

Kaplan-Meier curves showing cardiometabolic event-free survival stratified by cluster.

On the y-axis: probability of event-free survival without any cardiometabolic event, stratified by cluster membership. On the x-axis: Time from Exam 1 until und of follow-up (3 years after Exam 3) in days. Periods of Exam 2 and 3 are marked by dashed grey lines. Marked decreases during the examination periods are mainly due to newly identified T2D cases that were ascertained during the OGTT performed as part of the examinations. For the visualization of Kaplan-Meier curves, prevalent cardiometabolic events at Exam 1 were excluded, resulting in a sample size of n = 926 for men and n = 982 for women.

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Fig 4 Expand

Table 2.

Association between cluster membership and cardiometabolic events assessed by logistic regression models.

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Table 2 Expand