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Fig 1.

Patient selection flowchart.

AG: anion gap. ICU: intensive care unit. ICD10: tenth version of the International Classifcation of Disease. ICD9: ninth version of the International Classifcation of Disease.

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Table 1.

Characteristics of the study population between in-hospital survival and in-hospital mortality group.

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Fig 2.

Receiver-operating characteristic curves of the SOFA, ACAG, ALB and AG to predict in-hospital mortality among trauma patients.

SOFA: Sequential Organ Failure Assessment. ACAG: albumin corrected anion gap; ALB: albumin; AG: anion gap.

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Fig 3.

The best cutoff value of ACAG was taken by the K-M curve with log-rank test.

ACAG: albumin corrected anion gap.

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Fig 4.

Jitter plot of distribution of propensity scores (A). Histogram of distribution of propensity scores (B).

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Fig 5.

Standardized mean differences (SMDs) of variables before and after matching.

MAP: mean arterial pressure. Wbc: white blood cell. ACAG: albumin corrected anion gap. INR: international normalized ratio. PT: prothrombin time. GCS: Glasgow Coma Scale. PTT: partial thromboplastin time. SOFA: Sequential Organ Failure Assessment. SAPS Ⅱ: Simplified Acute Physiology Scores Ⅱ. APS Ⅲ: Acute Physiology Score Ⅲ. OASIS: Oxford Acute Severity of Illness Score.

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Table 2.

Characteristics of the study population were compared between low and high ACAG groups before and after PSM.

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Table 2 Expand

Table 3.

Subgroup analysis of the association between different levels of ACAG and in-hospital mortality.

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Table 3 Expand

Table 4.

Cox proportional hazard analysis of ACAG of in-hospital mortality in patients with trauma.

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Fig 6.

Kaplan—Meier survival curve of post-trauma patients with low level group of ACAG (blue curve. ACAG<20.375mmol/L) and high level group of ACAG (red curve. ACAG≥20.375mmol/L) at in-hospital(A, D), 30-day(B, E), 90-day(C, F) follow-up. (A-C)Reflect the results before PSM. (D-F)Reflect the results after PSM. ACAG: albumin corrected anion gap. PSM: propensity score matching.

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