Table 1.
The half maximal inhibitory concentrations of andrographolide, diclofenac, aspirin, paracetamol, and ibuprofen in LPS and IFN-γ induced PGE2, NO and TNF-α expressions in murine RAW264.7 cells.
Fig 1.
Dose-response curves of andrographolide compared with ibuprofen, aspirin, diclofenac, and paracetamol in inhibiting LPS and IFN-γ induced PGE2 (A), NO (B) and TNF-α (C) expressions on RAW264.7 cells. The data has been fitted using a log (inhibitor) vs. normalised response curve with variable slope model (n = 3). The error bar expresses the standard error of the mean.
Table 2.
The half maximal cytokines inhibitory concentrations of andrographolide, diclofenac, aspirin, paracetamol, and ibuprofen in LPS-induced THP-1 cells.
Fig 2.
Dose-response curves of andrographolide compared with ibuprofen, aspirin, diclofenac, and paracetamol in inhibiting NFκB (GFP) expressions on ELAM9-RAW264.7 cells measured by flow cytometry.
Error bars express standard error of the mean with n = 3 replicates.
Table 3.
The IC50 values of andrographolide, diclofenac, aspirin, paracetamol and ibuprofen in inhibiting ELAM9-RAW264.7 cells with NFκB green fluorescent protein (GFP).