Fig 1.
Flowchart of study inclusion.
Table 1.
Baseline characteristics of the studies.
Fig 2.
Forest plot about the pooled results of HAIC-FO plus TKI and ICIs for advanced HCC.
Outcome: ORR (A,B) and DCR (C,D) in total. ORR, objective response rate; DCR, disease control rate.
Fig 3.
Forest plot about the pooled mPFS in total with HAIC-FO plus TKI and ICIs for advanced HCC(A,B). mPFS, median progression-free survival.
Fig 4.
Forest plots for HAIC-FO plus TKI and ICIs for advanced HCC.
Outcomes: (A): OS; (B, C): PFS; (D): objective response rate (ORR), (E): disease control rate (DCR).
Fig 5.
Adverse events: Any grades (A) and grade 3/4(B) in total.