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Fig 1.

Flow diagram of study selection.

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Table 1.

Characteristics of the studies.

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Fig 2.

Results of the quality assessment of the retrieved modelling approaches based on the ISPOR “Questionnaire to assess relevance and credibility of modeling studies for informing health care decision making” [30].

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Table 2.

Incremental cost, life years gained, quality-adjusted life years and incremental cost-effectiveness ratios of 5-yearly sigmoidoscopy compared with commonly used screening measures (in 2019 $).

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Table 2 Expand

Table 3.

Incremental cost, life years gained, quality-adjusted life years and incremental cost-effectiveness ratios of 5-yearly sigmoidoscopy compared with newer screening measures (in 2019 $).

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Table 3 Expand

Table 4.

Incremental cost, life years gained, quality-adjusted life years and incremental cost-effectiveness ratios of 5-yearly sigmoidoscopy combined with annual stool tests compared with single measure strategies (in 2019 $).

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Table 4 Expand

Table 5.

Influential variables and indicators.

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Table 5 Expand